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stem cell therapy in old age painful conditions??

By : on : June 21, 2016 comments : (0)

Knee Pain and Injury

  • Stem cell injections for osteoarthritis in older patients

    We receive many questions regarding stem cell therapy for osteoarthritis conditions. One of the most most frequently asked are “am I too old for treatment? or, “Is my father (mother) too old for treatment?”

    The effects of age can be accounted for by doctors experienced in the treatment and understand the differences in the types of stem cells being collected for treatment.

    While age reduced overall cell yield and adipogenic potential (changing ability) of stem cells studied, osteogenesis (bone formation) and clonogenicity (the ability of cellls to  clone themselves)  remained unchanged. These findings indicate the importance of age as a factor when designing cell-based therapies for older patients.1

    Basically, find a doctor who know what they are doing when picking stem cells for aged parents or you.

    Mesenchymal stem cells in joint disease and repair

    Doctors note that Mesenchymal stem cells are known to have a potential for articular cartilage regeneration, however this favorable research is centered on surgical implant of the stem cells. Now doctors have found that for the treatment of generalized cartilage loss in osteoarthritis, an alternative delivery strategy would be more appropriate and that is injection therapy.3

    For those of us effected by osteoarthritis we know the impact it can have on quality of life. The research surrounding an effective treatment for osteoarthritis has yet to find an approved pharmacological intervention, biologic therapy or procedure that prevents the progressive destruction of the osteoarthritis joint. Stem cell injections for osteoarthritis (your own stem cells) can help maintenance healthy tissues by acting as repair cells or to reduce inflammation. The injection of Mesenchymal stem cells has produced promising outcomes in preclinical models of joint disease.4


    Researching stem cell injections for osteoarthritis

    In dealing with knee osteoarthritis, research notes that conventional treatments for osteoarthritis have demonstrated only modest clinical benefits and without cartilage repair. However, what research is also confirming is that stem cell therapies have shown encouraging results. They have confirmed feasibility and safety and strong indications of clinical efficacy were identified. Patients exhibited rapid and progressive improvement. . . “Stem Cell therapy may be a valid alternative treatment for chronic knee osteoarthritis. The intervention is simple, does not require hospitalization or surgery, provides pain relief, and significantl


    What is Stem Cell Therapy?

    Stem cells are derived from the patient. Mesenchymal stem cells are found in the bone marrow, fat, and possibly in other tissues and are responsible for rebuilding and regenerating the body.

    These stem cells help the body renew and heal itself. Mesenchymal stem cells are also able to differentiate into ligaments, tendons, and cartilage, and maintain a special role in the non-surgical treatment of osteoarthritis, treatment of chronic pain, and sports injuries.

    What is so promising is that that stem cells may have the potential to prevent a knee, hip, shoulder or ankle replacement or fusion, repair a torn rotator cuff or labrum, and heal a meniscus tear of the knee. Our body possesses the power of repair in the stem cell, but it often will need to be concentrated in an area of injury or chronic degeneration to be truly effective.

    Symptoms associated with the following conditions possibly treated by Stem cell injections for osteoarthritis:

    • Rotator cuff tendonitis
    • Biceps tendonitis
    • Osteochondral defects
    • Osteochondritis dessicans
    • Labral tears of the hip and shoulder
    • Chronic epicondylitis (tennis and golfer’s elbow)
    • Non-healing fractures
    • Osteoarthritis
    • Ligament injuries
    • Degenerative disc disease
    • Sciatica
    • Chronic neck and back pain
    • Headaches
    • Post concussion syndrome
    • TMJ
    • Chronic groin and hamstring strains
    • avascular necrosis of the hip

    Stem cell therapy is performed by extracting stem cells from the body, thats autologus purifying them, and then injecting them back into the damaged area. The stem cells cannot work alone, and they require help from growth and support factors found in other tissues and blood.

    We follow strict FDA guidelines in the use of stem cells, and at no time do we manipulate, expand, or grow stem cells in culture. We believe the best stem cell therapies are derived from the patient in high concentration, and placed back into the area of treatment. Manipulation and replication of stem cells in culture may inactivate these cells and may also lead to the development a of mutation that could lead to cancer. The use of the patient’s own adult stem cells, as is performed at the jaipur pain relief centre, avoids this problem.

    The area of injury or arthritis is treated with both stem cells and platelet rich plasma (PRP). If stem cells are the seeds in the lawn, PRP is the fertilizer that helps the lawn grow. PRP, a combination of growth factors and platelets naturally found in the body, provides cell signals and nourishment to help the stem cells flourish and develop into new joints, ligaments, tendons, and other body parts. PRP not only triggers stem cell development, but can also help stem cells regenerate on their own inside the body, and can also attract circulating stem cells to the area of injury. We have used PRP alone in the treatment of many injuries and pain problems.

    Most cases of stem cell and PRP treatments are successful, and avoid the pain, disability, down time, and risk associated with major surgery. There is minimal recovery from a stem cell or PRP treatment, usually mediated by soreness in the area that was treated, and there is also a risk of bruising. There have been no reports of serious adverse effects in the scientific literature when adult mesenchymal stem cells are used in these procedures. Afterwards, the patient is encouraged to use the joint normally, and follow up treatments of PRP are given in 4-6 weeks intervals to continue to allow the stem cells to do their work. Since stem cell treatment is very safe, it can be repeated in the joint if necessary to obtain optimal results. Also, having treatment with stem cells would not make a person ineligible for surgery.

    Our treatment plan of joint injuries and chronic pain is also unique when compared to other practices., in the non-surgical treatment of joint injuries,  This experience allows us to take a dual approach to joint injury with the use of stem cells and PRP to treat within the joint, and the use of prolotherapy to strengthen and regenerate the supporting structure of the joint. A holistic view of orthopaedics is also followed in several ways, as we look not only at the injured joint, but at where the problem originates, whether that is with a tilt in the pelvis, abnormal gait (walking cycle), spinal misalignment or, for example, with acquired weakness in the foot leading to excessive pronation and a drop in the arch.

    where a full discussion of diet, exercise, lifestyle, and supplementation is reviewed. We employ medical weight management programs if necessary to help take pressure off the joint. We believe a comprehensive and cohesive approach to joint injury will yield the greatest results and help to prevent surgery. We have had the opportunity to treat anyone from professional athletes to patients who have suffered for decades with chronic pain, and invite you to schedule a consultation with us to see how we can help you.woman-in-red-shirt-holding-her-knee

sanjay sharma

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